Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701624 | 0.84 | ASPH (0.34) | IDO1 | |
| SCHEMBL30426481 | 0.84 | ASPH (0.34) | IDO1 | |
| SCHEMBL12902771 | 0.69 | — | — | |
| SCHEMBL12946093 | 0.68 | HPGD (0.32) | IDO1 | |
| SCHEMBL29317925 | 0.68 | — | — | |
| SCHEMBL10197339 | 0.65 | HSP90AA1 (0.36) | — | |
| SCHEMBL17552426 | 0.65 | ALDH1A1 (0.42) | — | |
| SCHEMBL2374756 | 0.64 | — | — | |
| SCHEMBL7841178 | 0.64 | — | — | |
| SCHEMBL115676 | 0.64 | AURKA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004299-A1 | TETRAHYDRO-PYRIDO-PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |