Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 5/20 | 0.50 |
| ▸ | ERN1 | O75460 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16769649 | 1.00 | RXRA (0.54) | RXRAHSD17B10EGFRRXRBERN1 | |
| SCHEMBL12535966 | 1.00 | RXRA (0.54) | RXRAHSD17B10EGFRRXRBERN1 | |
| SCHEMBL15119807 | 0.97 | RXRA (0.51) | RXRAHSD17B10EGFRRXRBERN1 | |
| SCHEMBL12780511 | 0.94 | HSD17B10 (0.56) | RXRAHSD17B10RXRBERN1TRIM24 | |
| SCHEMBL15132369 | 0.92 | RXRA (0.56) | RXRAHSD17B10EGFRRXRBERN1 | |
| SCHEMBL20022593 | 0.91 | RXRA (0.46) | RXRAHSD17B10EGFRRXRBERN1 | |
| SCHEMBL20022592 | 0.91 | RXRA (0.46) | RXRAHSD17B10EGFRRXRBERN1 | |
| SCHEMBL18504207 | 0.90 | HSD17B10 (0.49) | RXRAHSD17B10EGFRRXRBERN1 | |
| SCHEMBL18504197 | 0.89 | HSD17B10 (0.51) | RXRAHSD17B10RXRBERN1TRIM24 | |
| SCHEMBL18504198 | 0.89 | HSD17B10 (0.51) | RXRAHSD17B10RXRBERN1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230375235-A1 | ADSORPTION HEAT PUMP | DAIKIN INDUSTRIES, LTD. (JP) | 2023-11-23 | — | — | US | disclosed |
| US-8946454-B2 | Chemical framework compositions and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-03 | — | — | US | disclosed |
| US-8841471-B2 | Open metal organic frameworks with exceptional surface area and high gas storage capacity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-23 | — | — | US | disclosed |
| US-20120172612-A1 | OPEN METAL ORGANIC FRAMEWORKS WITH EXCEPTIONAL SURFACE AREA AND HIGH GAS STORAGE CAPACITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-05 | — | — | US | disclosed |
| US-20110137025-A1 | CHEMICAL FRAMEWORK COMPOSITIONS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172612-A1 | OPEN METAL ORGANIC FRAMEWORKS WITH EXCEPTIONAL SURFACE AREA AND HIGH GAS STORAGE CAPACITY | EPCAM, SLCO1A2, SLCO2A1 | RXRA 1329/4885HSD17B10 2931/4885EGFR 1702/4885 |
| US-20110137025-A1 | CHEMICAL FRAMEWORK COMPOSITIONS AND METHODS OF USE | CA6, EPCAM, CA12 | RXRA 396/4885HSD17B10 4329/4885EGFR 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.