SCHEMBL1026085

SCHEMBL1026085

CC(C)C(C(=O)O)(C(=O)O)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
TP53 P04637 2/20 0.39
CYP2D6 P10635 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 2/20 0.33
SLC7A5 Q01650 1/20 0.32
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
HIF1A Q16665 2/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21268957 0.97 ALDH1A1 (0.37) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL28315717 0.97 ALDH1A1 (0.37) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL21269969 0.97 ALDH1A1 (0.37) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL21269237 0.97 ALDH1A1 (0.37) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL28875915 0.97 ALDH1A1 (0.37) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL28314490 0.97 ALDH1A1 (0.37) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL28314661 0.94 ALDH1A1 (0.35) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL29013924 0.84 ALDH1A1 (0.33) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL7824300 0.82 CYP1A2 (0.35) ALDH1A1TSHRTP53CYP2D6CYP1A2
SCHEMBL28354980 0.82 TP53 (0.32) ALDH1A1TSHRTP53CYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3771720-B1 BLOCKED POLYISOCYANATE COMPOSITION, RESIN COMPOSITION, RESIN FILM AND LAMINATE ASAHI CHEMICAL IND (JP) 2024-05-01 EP claimed
EP-4289878-A1 ONE-COMPONENT SYSTEM COMPRISING BLOCKED POLYURETHANE PREPOLYMERS Evonik Operations GmbH (DE) 2023-12-13 EP claimed
EP-3438149-B1 BLOCK POLYISOCYANATE COMPOSITION, ONE-PART COATING COMPOSITION, COATING FILM, AND COATED ARTICLE ASAHI CHEMICAL IND (JP) 2021-06-09 EP claimed
EP-2496649-B2 FILM-FORMING COMPOSITION CONTAINING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE SAINT GOBAIN ADFORS (FR) 2020-10-28 EP claimed
EP-3053935-B1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME CHINA PETROLEUM & CHEM CORP (CN) 2019-05-08 EP claimed
EP-2268589-B1 SIZING COMPOSITION FOR MINERAL FIBERS AND RESULTING PRODUCTS SAINT GOBAIN ISOVER (FR) 2018-06-13 EP claimed
EP-2438025-B1 MINERAL FIBER MAT CONTAINING A FORMALDEHYDE-TRAPPING AGENT, AND METHODS FOR MANUFACTURING SAME SAINT-GOBAIN ADFORS (FR) 2017-12-27 EP claimed
CN-104513332-B Catalyst system and its application for olefinic polymerization 中国石油化工股份有限公司 2017-06-06 CN claimed
EP-2349944-B1 PROCESS FOR MANUFACTURING INSULATION PRODUCTS BASED ON MINERAL WOOL, AND PRODUCTS OBTAINED SAINT GOBAIN ISOVER (FR) 2017-05-17 EP claimed
EP-2913335-B1 ANTI-TUMOR BIVALENT PLATINUM COMPLEX AND PREPARATION METHOD FOR COMPLEX AND LIGAND OF COMPLEX UNIV SOUTHEAST (CN) 2017-03-29 EP claimed
EP-1366057-B1 METHOD FOR DEPROTECTING OLIGONUCLEOTIDES APPLERA CORP (US) 2005-12-14 EP claimed
US-20040191808-A1 Reagents for oligonucleotide cleavage and deprotection APPLERA CORPORATION 2004-09-30 US claimed
EP-1366057-A4 REAGENTS FOR OLIGONUCLEOTIDE CLEAVAGE AND DEPROTECTION APPLERA CORP (US) 2004-04-14 EP claimed
US-6664388-B2 Reacting protected oligonucleotide containing at least one 2-cyanoethyl phosphate internucleotide linkage with deprotection reagent comprising active methylene compound and amine reagent to remove protecting groups APPLERA CORPORATION 2003-12-16 US claimed
EP-1366057-A2 REAGENTS FOR OLIGONUCLEOTIDE CLEAVAGE AND DEPROTECTION Applera Corporation (US) 2003-12-03 EP claimed
US-20030181712-A1 REAGENTS FOR OLIGONUCLEOTIDE CLEAVAGE AND DEPROTECTION PE CORPORATION (NY) (US) 2003-09-25 US claimed
WO-2002072864-A2 REAGENTS FOR OLIGONUCLEOTIDE CLEAVAGE AND DEPROTECTION APPLERA CORPORATION (US) 2002-09-19 WO claimed
EP-0062119-B1 PROCESS OF PRODUCING 1,3-DITHIOL-2-YLIDENE MALONIC ACID DIALKYL ESTERS NIHON NOHYAKU CO., LTD. (JP) 1986-01-02 EP claimed
EP-0050762-B1 PROCESS FOR THE PREPARATION OF VINYLCYCLOPROPANE DERIVATIVES NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1984-06-13 EP claimed
EP-0025846-B1 IMPROVED PROCESS FOR THE PREPARATION OF VINYLCYCLOPROPANE DERIVATIVES NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1984-03-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181712-A1 REAGENTS FOR OLIGONUCLEOTIDE CLEAVAGE AND DEPROTECTION OGG1, MPG, NSUN2 ALDH1A1 944/4885TSHR 1731/4885TP53 4123/4885
US-20040191808-A1 Reagents for oligonucleotide cleavage and deprotection OGG1, MPG, NSUN2 ALDH1A1 944/4885TSHR 1731/4885TP53 4123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.