Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 11/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904106 | 0.90 | AHCY (0.45) | AHCYNAMPTPARP1KCNH2TMEM97 | |
| SCHEMBL11903758 | 0.90 | AHCY (0.45) | AHCYNAMPTPARP1KCNH2TMEM97 | |
| SCHEMBL1027797 | 0.85 | AHCY (0.45) | AHCYNAMPTPARP1GPR119KCNH2 | |
| SCHEMBL11975714 | 0.85 | AHCY (0.48) | AHCYNAMPTDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL1027771 | 0.84 | AHCY (0.49) | AHCYNAMPTDPP8DPP9 | |
| SCHEMBL1197610 | 0.84 | NAMPT (0.33) | AHCYNAMPTDPP4KCNH2TMEM97 | |
| SCHEMBL11895600 | 0.81 | AHCY (0.46) | AHCYNAMPTKCNH2TMEM97SIGMAR1 | |
| SCHEMBL11896239 | 0.78 | AHCY (0.41) | AHCYNAMPTPARP1GPR119 | |
| SCHEMBL11973982 | 0.78 | AHCY (0.56) | AHCY | |
| SCHEMBL1027953 | 0.78 | AHCY (0.35) | AHCYNAMPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |