Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 11/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026232 | 0.85 | AHCY (0.45) | AHCYGPR119PARP1NAMPTKCNH2 | |
| SCHEMBL11975701 | 0.85 | AHCY (0.48) | AHCYNAMPT | |
| Hydrochloric Acid SCHEMBL1026455 | 0.84 | AHCY (0.49) | AHCYNAMPT | |
| SCHEMBL11903758 | 0.84 | AHCY (0.45) | AHCYPARP1NAMPTKCNH2TMEM97 | |
| SCHEMBL11904106 | 0.84 | AHCY (0.45) | AHCYPARP1NAMPTKCNH2TMEM97 | |
| SCHEMBL11974073 | 0.84 | AHCY (0.40) | AHCYNAMPT | |
| SCHEMBL1197343 | 0.83 | GPR119 (0.33) | AHCYGPR119NAMPTKCNH2TMEM97 | |
| SCHEMBL11975712 | 0.82 | AHCY (0.48) | AHCYNAMPT | |
| SCHEMBL11975175 | 0.81 | AHCY (0.47) | AHCYNAMPT | |
| SCHEMBL11983479 | 0.81 | DPP9 (0.35) | AHCYNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |