Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27670383 | 0.86 | GAA (0.43) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL21428418 | 0.86 | HTR1A (0.44) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL12658314 | 0.85 | MAPT (0.39) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28938071 | 0.84 | TSHR (0.39) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL28722507 | 0.84 | TSHR (0.39) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL5407237 | 0.82 | MEN1 (0.52) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL13609329 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL3768429 | 0.81 | KMT2A (0.55) | TSHRALDH1A1POLBMAPTMEN1 | |
| SCHEMBL17092977 | 0.81 | MEN1 (0.41) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL27800842 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |