Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 6/20 | 0.48 |
| ▸ | RXRA | P19793 | 9/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10264164 | 0.85 | RXRA (0.50) | KAT6ARXRAGRIN1GRIN2BKDM4E | |
| SCHEMBL12988634 | 0.85 | KAT6A (0.46) | KAT6ARXRAGRIN1GRIN2BKDM4E | |
| SCHEMBL12988322 | 0.82 | ALDH1A1 (0.43) | KAT6ARXRAGRIN1GRIN2BKDM4E | |
| SCHEMBL22779385 | 0.81 | KAT6A (0.46) | KAT6ARXRAGRIN1GRIN2BKDM4E | |
| SCHEMBL18311247 | 0.80 | KAT6A (0.61) | KAT6AKDM4EMAPTKMT2ANPC1 | |
| SCHEMBL12349894 | 0.79 | GRM4 (0.43) | KAT6AKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL31517335 | 0.79 | MEN1 (0.40) | RXRAGRIN1GRIN2BKDM4EMAPT | |
| SCHEMBL2609429 | 0.78 | RXRA (0.41) | KAT6ARXRAGRIN1GRIN2B | |
| SCHEMBL25551413 | 0.78 | NOTUM (0.46) | KAT6AKDM4EMAPTMAPK1NPSR1 | |
| SCHEMBL3143610 | 0.77 | NPC1 (0.50) | KAT6ARXRAGRIN1GRIN2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785445-B2 | 7-phenoxychroman carboxylic acid derivatives | ARRAY BIOPHARMA INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120101103-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC. (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101103-A1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | PTGDR2, PTGDR, HRH2 | KAT6A 3581/4885RXRA 194/4885GRIN1 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.