Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 2/20 | 0.32 |
| ▸ | KCNT1 | Q5JUK3 | 4/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1025721 | 0.99 | HDAC4 (0.39) | HDAC4AHCYNAMPTTP53MAPT | |
| Hydrochloric Acid SCHEMBL1027066 | 0.94 | HDAC4 (0.39) | HDAC4AHCYNAMPTNPY2RKCNT1 | |
| Hydrochloric Acid SCHEMBL1026270 | 0.92 | HDAC4 (0.37) | HDAC4TP53MAPTKCNT1 | |
| Hydrochloric Acid SCHEMBL1026411 | 0.87 | HDAC4 (0.37) | HDAC4KCNT1 | |
| SCHEMBL1026274 | 0.86 | HDAC4 (0.35) | HDAC4AHCYNAMPTTP53MAPT | |
| SCHEMBL1197482 | 0.84 | AHCY (0.35) | AHCYNAMPTTP53MAPTHPGD | |
| SCHEMBL11975774 | 0.83 | AHCY (0.50) | HDAC4AHCYNAMPTNPY2RTSHR | |
| Hydrochloric Acid SCHEMBL1024812 | 0.82 | AHCY (0.39) | AHCYNAMPTTP53MAPT | |
| SCHEMBL1196620 | 0.80 | HDAC4 (0.34) | HDAC4TP53MAPTNPY2RKCNT1 | |
| SCHEMBL1026993 | 0.80 | AHCY (0.39) | AHCYNAMPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |