Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 8/20 | 0.34 |
| ▸ | HTR1B | P28222 | 7/20 | 0.34 |
| ▸ | HTR2A | P28223 | 7/20 | 0.34 |
| ▸ | KIFC1 | Q9BW19 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1024812 | 0.90 | AHCY (0.39) | AHCYMAPK14NAMPTMAPTKIFC1 | |
| Hydrochloric Acid SCHEMBL1027066 | 0.90 | HDAC4 (0.39) | AHCYNAMPT | |
| SCHEMBL1026432 | 0.84 | HDAC4 (0.39) | AHCYNAMPTMAPTTP53HPGD | |
| Hydrochloric Acid SCHEMBL1025721 | 0.84 | HDAC4 (0.39) | AHCYNAMPTMAPTTP53HPGD | |
| Hydrochloric Acid SCHEMBL1026411 | 0.83 | HDAC4 (0.37) | — | |
| SCHEMBL1026096 | 0.83 | AHCY (0.39) | AHCYNAMPTMEN1ALDH1A1TP53 | |
| SCHEMBL11974823 | 0.82 | AHCY (0.53) | AHCYMAPK14NAMPTKIFC1TP53 | |
| Hydrochloric Acid SCHEMBL1027656 | 0.82 | AHCY (0.41) | AHCYNAMPTMAPTMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1028429 | 0.81 | NAMPT (0.34) | AHCYNAMPTMAPTHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL1028342 | 0.81 | AHCY (0.35) | AHCYALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-02-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | BHMT, CBS, BHMT2 | AHCY 4/4885MAPK14 2008/4885NAMPT 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.