Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 9/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13562313 | 0.85 | HRH4 (0.59) | HRH4HRH3 | |
| SCHEMBL10263146 | 0.77 | HRH4 (0.64) | HRH4HRH3 | |
| SCHEMBL1006834 | 0.76 | ALOX15 (0.48) | HPGD | |
| SCHEMBL10263385 | 0.75 | HRH4 (0.74) | HRH4HRH3SIGMAR1HPGDHSP90AA1 | |
| SCHEMBL10263701 | 0.75 | HRH4 (0.69) | HRH4HRH3SIGMAR1HPGDHSP90AA1 | |
| SCHEMBL10264424 | 0.71 | HRH4 (0.47) | HRH4HRH3SIGMAR1HSP90AA1RHEB | |
| SCHEMBL10264652 | 0.70 | HRH4 (0.49) | HRH4HRH3SIGMAR1HSP90AA1RHEB | |
| SCHEMBL10263610 | 0.70 | HRH4 (0.49) | HRH4HRH3SIGMAR1HSP90AA1RHEB | |
| SCHEMBL13562341 | 0.69 | HRH4 (0.47) | HRH4HRH3SIGMAR1HSP90AA1RHEB | |
| SCHEMBL13562353 | 0.69 | HRH4 (0.47) | HRH4HRH3SIGMAR1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460794-A1 | PHARMACEUTICAL COMPOSITION CONTAINING FUSED HETERO-RING DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |