Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12616280 | 0.81 | MAPT (0.66) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL1793013 | 0.81 | ALDH1A1 (0.52) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL1791337 | 0.79 | MEN1 (0.45) | MAPTLMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9909759 | 0.78 | SMN1; SMN2 (0.47) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL1796033 | 0.78 | MAPT (0.45) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL9909773 | 0.76 | TNKS (0.47) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL13667119 | 0.74 | MAPT (0.43) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL1791998 | 0.74 | ALDH1A1 (0.54) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL4471803 | 0.74 | ALDH1A1 (0.54) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL13603224 | 0.73 | LMNA (0.63) | MAPTLMNAALDH1A1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013207-B1 | IMIDAZO[4,5-B]PYRIDIN-2-ONE COMPOUNDS AND ANALOGS THEREOF AS CANCER THERAPEUTIC COMPOUNDS | CANCER REC TECH LTD (GB) | 2012-04-25 | — | — | EP | disclosed |