Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.58 |
| ▸ | BAX | Q07812 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410834 | 0.87 | DNM1 (0.73) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL12013711 | 0.82 | DNM1 (0.68) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL411949 | 0.81 | DNM1 (0.66) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL30939889 | 0.81 | DNM1 (0.66) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL15592978 | 0.81 | DNM1 (0.70) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL16099375 | 0.80 | DNM1 (0.67) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL409802 | 0.80 | DNM1 (0.62) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL411279 | 0.79 | KMT2A (0.78) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL6819686 | 0.78 | BAX (0.82) | DNM1MAPTSMN1; SMN2P2RX3BAX | |
| SCHEMBL16923669 | 0.78 | DNM1 (0.67) | DNM1MAPTSMN1; SMN2P2RX3BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006419-A2 | PRO-NEUROGENIC COMPOUNDS | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-01-12 | — | — | WO | disclosed |