SCHEMBL1026465

SCHEMBL1026465

C=Cc1ccc(CSCCO)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
CYP2C19 P33261 2/20 0.35
TDP1 Q9NUW8 2/20 0.34
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PTGER1 P34995 1/20 0.32
PTGER4 P35408 1/20 0.32
PTGER3 P43115 1/20 0.32
PTGER2 P43116 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C9 P11712 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745221 0.90 LTA4H (0.36) ALDH1A1CYP2C19TSHRCHRNB2CHRNB4
SCHEMBL7089052 0.89 ALDH1A1 (0.39) ALDH1A1CYP2C19TDP1TSHRPOLB
SCHEMBL8745127 0.89 ALDH1A1 (0.33) ALDH1A1TDP1CHRNB2CHRNB4CHRNA3
SCHEMBL6389194 0.88 ALDH1A1 (0.50) ALDH1A1CYP2C19TDP1TSHRPOLB
SCHEMBL6392514 0.84 ALDH1A1 (0.46) ALDH1A1CYP2C19TDP1TSHRPOLB
SCHEMBL5066949 0.83 ALDH1A1 (0.55) ALDH1A1CYP2C19TDP1TSHRPOLB
SCHEMBL4106407 0.83 TDP1 (0.47) ALDH1A1CYP2C19TDP1HPGDMEN1
SCHEMBL14732603 0.81 ALDH1A1 (0.42) ALDH1A1CYP2C19TSHRPOLBCHRNB2
SCHEMBL8745149 0.81 ALDH1A1 (0.42) ALDH1A1CYP2C19TSHRPOLBMEN1
SCHEMBL6393296 0.79 ALDH1A1 (0.41) ALDH1A1CYP2C19TSHRPOLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106118333-B Aqueous protection spray film 广州驰彩汽车科技有限公司 2018-06-26 CN claimed
JP-9165422-A None JP disclosed
JP-9165426-A None JP disclosed
JP-9165423-A None JP disclosed
CN-111393683-B Modified cationic microgel and preparation method and application thereof 广东科德环保科技股份有限公司 2023-05-23 CN disclosed
CN-106118333-B Aqueous protection spray film 广州驰彩汽车科技有限公司 2018-06-26 CN disclosed
CN-106118333-A Novel aqueous protection spray film 广州驰彩汽车科技有限公司 2016-11-16 CN disclosed
US-8642718-B2 Curable composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-02-04 US disclosed
EP-1882713-B1 CURABLE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2013-07-03 EP disclosed
US-8394920-B2 Composition for resin and optical lens obtained therefrom MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-03-12 US disclosed
JP-H09165423-A COMPOSITION FOR PLASTIC LENS MITSUBISHI RAYON CO LTD 1997-06-24 JP disclosed
EP-0553801-B1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS (JP) 1997-04-23 EP disclosed
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP disclosed
US-5389708-A Polymerizing polyisocyanate or polyisothiocyanate with polyol or polythiol in presence of thiophosphoric or dithiophosphoric acid ester MITSUI TOATSU CHEMICALS, INC. (JP) 1995-02-14 US disclosed
US-5278267-A Water insoluble vinyl aromatic polymer EASTMAN KODAK COMPANY (US) 1994-01-11 US disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5210289-A Homo or coploymers for medical diagnosis EASTMAN KODAK COMPANY (US) 1993-05-11 US disclosed
US-5149737-A Carboxy group extended from polymer surface allows easier attachment of biological substances EASTMAN KODAK COMPANY (US) 1992-09-22 US disclosed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP disclosed
US-5034492-A Radiation transparent polymers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-07-23 US disclosed