Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15228229 | 0.78 | PIK3CD (0.48) | INMTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5573164 | 0.76 | INMT (0.38) | INMTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5416603 | 0.76 | ACE (0.45) | INMTGAAACEL3MBTL1CHRNA7 | |
| SCHEMBL11604283 | 0.76 | INMT (0.38) | INMTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9611931 | 0.76 | CYP3A4 (0.41) | INMTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1091230 | 0.76 | INMT (0.38) | INMTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL14275832 | 0.76 | CYP3A4 (0.41) | INMTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18883363 | 0.74 | PER2 (0.44) | INMTGAAACEL3MBTL1CHRNA7 | |
| Hydrochloric Acid SCHEMBL320458 | 0.74 | CYP3A4 (0.39) | INMTGAAACEL3MBTL1CHRNA7 | |
| Hydrochloric Acid SCHEMBL15123892 | 0.74 | CYP3A4 (0.39) | INMTGAAACEL3MBTL1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006055-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-01-12 | — | — | WO | disclosed |