Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627388 | 0.87 | SLC6A9 (0.47) | SLC6A9HTR1AHTR7ALDH1A1F2 | |
| SCHEMBL627013 | 0.83 | HTR1A (0.48) | SLC6A9HTR1AHTR7ALDH1A1MEN1 | |
| SCHEMBL627138 | 0.80 | SLC6A9 (0.46) | SLC6A9HTR1AHTR7ALDH1A1F2 | |
| SCHEMBL626932 | 0.79 | HTR1A (0.46) | SLC6A9HTR1AHTR7ALDH1A1F2 | |
| SCHEMBL626794 | 0.79 | SLC6A9 (0.48) | SLC6A9HTR1AHTR7ALDH1A1F2 | |
| SCHEMBL626911 | 0.79 | HTR1A (0.44) | SLC6A9HTR1AHTR7ALDH1A1MEN1 | |
| SCHEMBL626727 | 0.78 | SLC6A9 (0.44) | SLC6A9HTR1AHTR7ALDH1A1KMT2A | |
| SCHEMBL627436 | 0.78 | HTR1A (0.47) | SLC6A9HTR1AHTR7ALDH1A1MEN1 | |
| SCHEMBL626894 | 0.77 | HTR1A (0.46) | SLC6A9HTR1AHTR7ALDH1A1MEN1 | |
| SCHEMBL627278 | 0.77 | HTR1A (0.46) | SLC6A9HTR1AHTR7ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020130-A1 | PHENALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2012-02-16 | — | — | WO | disclosed |