Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627436 | 0.81 | HTR1A (0.47) | MTNR1AMTNR1BALDH1A1HTR1AHTR7 | |
| SCHEMBL867632 | 0.80 | SLC6A9 (0.50) | SLC6A9KCNH2MEN1KMT2ALMNA | |
| SCHEMBL626869 | 0.71 | HTR1A (0.43) | ALDH1A1HTR1AHTR7SLC6A9HTT | |
| SCHEMBL12473893 | 0.71 | TAAR1 (0.44) | MTNR1AMTNR1BALDH1A1KMT2ALMNA | |
| SCHEMBL867654 | 0.70 | SLC6A9 (0.55) | ALDH1A1SLC6A9KCNH2MEN1KMT2A | |
| SCHEMBL627013 | 0.70 | HTR1A (0.48) | MTNR1AMTNR1BALDH1A1HTR1AHTR7 | |
| SCHEMBL628190 | 0.69 | SLC6A9 (0.53) | ALDH1A1SLC6A9KCNH2MEN1KMT2A | |
| SCHEMBL627155 | 0.68 | SLC6A9 (0.49) | ALDH1A1HTR1AHTR7SLC6A9KCNH2 | |
| SCHEMBL626894 | 0.68 | HTR1A (0.46) | ALDH1A1HTR1AHTR7SLC6A9KCNH2 | |
| SCHEMBL627278 | 0.68 | HTR1A (0.46) | ALDH1A1HTR1AHTR7SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020130-A1 | PHENALKYLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2012-02-16 | — | — | WO | disclosed |