Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38657150 | 1.00 | TDP1 (0.64) | TDP1HTTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL31075422 | 0.85 | HTT (0.66) | TDP1HTTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL446056 | 0.85 | HTT (0.66) | TDP1HTTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL23255814 | 0.85 | HSPB1 (0.49) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL8066340 | 0.85 | TDP1 (0.44) | TDP1HTTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL527567 | 0.82 | HTT (0.72) | TDP1HTTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL29441283 | 0.82 | HTT (0.72) | TDP1HTTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL17467709 | 0.81 | TDP1 (0.46) | TDP1HTTLMNASMN1; SMN2MEN1 | |
| SCHEMBL13578458 | 0.81 | TDP1 (0.42) | TDP1HTTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL4962536 | 0.81 | MAPT (0.55) | TDP1HTTLMNASMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117913367-A | Preparation method of composite organic solvent, electrolyte and lithium-sulfur battery | 东方电气集团科学技术研究院有限公司 | 2024-04-19 | — | — | CN | claimed |
| WO-2024244972-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-12-05 | — | — | WO | disclosed |
| CN-117913367-A | Preparation method of composite organic solvent, electrolyte and lithium-sulfur battery | 东方电气集团科学技术研究院有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-20240050576-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2024-02-15 | — | — | US | disclosed |
| CN-117362642-A | Polyimide with high Tg and low dielectric constant, and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2024-01-09 | — | — | CN | disclosed |
| EP-4285906-A2 | AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF | Epizyme Inc (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20230359119-A1 | RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-11-09 | — | — | US | disclosed |
| EP-3555070-B1 | AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF | EPIZYME INC (US) | 2023-08-09 | — | — | EP | disclosed |
| US-20230149550-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| US-20230149550-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2023-05-18 | — | — | US | disclosed |
| CN-1835923-A | Process for preparing 4-amino-3-quinolinecarbonitriles | WYETH CORP (US) | 2006-09-20 | — | — | CN | disclosed |
| EP-1660453-A2 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-QUINOLINECARBONITRILES | Wyeth Holdings Corporation (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2006055734-A2 | 3-PHENYL-PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2006017443-A2 | ARYL-AMINO SUBSTITUTED PYRROLOPYRIMIDINE MULTI-KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2006-02-16 | — | — | WO | disclosed |
| US-6943257-B2 | Process for preparation of aromatic halides from aromatic amines | BAIK WOON PHIL (KR) | 2005-09-13 | — | — | US | disclosed |
| US-20050065195-A1 | Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors | GLAXO GROUP LIMITED (GB) | 2005-03-24 | — | — | US | disclosed |
| WO-2005019201-A2 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-QUINOLINECARBONITRILES | WYETH HOLDINGS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050043537-A1 | Process for preparation of 4-amino-3-quinolinecarbonitriles | WYETH HOLDINGS CORPORATION (US) | 2005-02-24 | — | — | US | disclosed |
| US-20040092728-A1 | Process for preparation of aromatic halides from aromatic amines | BAIK WOON PHIL (KR) | 2004-05-13 | — | — | US | disclosed |
| WO-2002053545-A1 | PROCESS FOR PREPARATION OF AROMATIC HALIDES FROM AROMATIC AMINES | BAIK WOON PHIL (KR) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065195-A1 | Oxadiazolyl-biphenylcarboxamides and their use as p38 kinase inhibitors | MAPK3, MAPK1, MAPKAPK3 | TDP1 1963/4885HTT 4796/4885LMNA 3783/4885 |
| US-20230149550-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | DMPK, DTYMK, MYCBP | TDP1 70/4885HTT 32/4885LMNA 136/4885 |
| US-20050043537-A1 | Process for preparation of 4-amino-3-quinolinecarbonitriles | BTF3, PTMS, BCAT2 | TDP1 2490/4885HTT 3170/4885LMNA 2391/4885 |
| US-20040092728-A1 | Process for preparation of aromatic halides from aromatic amines | AHR, CYC1, HCCS | TDP1 1855/4885HTT 335/4885LMNA 2546/4885 |
| US-20240050576-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | ZFX, GRN, F13B | TDP1 258/4885HTT 53/4885LMNA 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.