SCHEMBL10270627

SCHEMBL10270627

CCC(CO/N=C1\CCCc2ccc(C)nc21)CO/N=C1\CCCc2ccc(C)nc21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.34
PKM P14618 1/20 0.34
GRM5 P41594 1/20 0.32
RAB9A P51151 2/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10270632 0.92
SCHEMBL10271161 0.89 L3MBTL1 (0.34) L3MBTL1PKMGRM5RAB9ALMNA
SCHEMBL10270623 0.88 L3MBTL1 (0.35) L3MBTL1PKMGRM5RAB9ALMNA
SCHEMBL10270639 0.88 L3MBTL1 (0.34) L3MBTL1PKMGRM5RAB9ALMNA
SCHEMBL10271000 0.88 L3MBTL1 (0.36) L3MBTL1PKMGRM5RAB9ALMNA
SCHEMBL10271151 0.85 L3MBTL1 (0.34) L3MBTL1PKMGRM5
SCHEMBL10271160 0.83 L3MBTL1 (0.34) L3MBTL1PKMGRM5RAB9ALMNA
SCHEMBL15771466 0.83 L3MBTL1 (0.32) L3MBTL1PKM
SCHEMBL10271150 0.82 L3MBTL1 (0.34) L3MBTL1PKMGRM5RAB9ALMNA
SCHEMBL15783252 0.82 L3MBTL1 (0.36) L3MBTL1PKMGRM5RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2014-06-12 US disclosed
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2014-06-12 US disclosed
WO-2012013754-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES PRDX4, PRDX6, DDT L3MBTL1 773/4885PKM 1289/4885GRM5 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.