Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6385399 | 0.98 | KDM4E (0.60) | KDM4EALOX15SMN1; SMN2MAPTMAOB | |
| SCHEMBL10339724 | 0.86 | KDM4E (0.56) | KDM4EALOX15SMN1; SMN2MAPTMAOB | |
| SCHEMBL21836463 | 0.84 | MAOB (0.51) | KDM4EALOX15SMN1; SMN2MAPTMAOB | |
| SCHEMBL28205795 | 0.84 | ALOX15 (0.50) | KDM4EALOX15SMN1; SMN2MAPTMAOB | |
| SCHEMBL4036348 | 0.84 | KDM4E (0.54) | KDM4EALOX15SMN1; SMN2MAPTMAOB | |
| SCHEMBL4036347 | 0.84 | KDM4E (0.54) | KDM4EALOX15SMN1; SMN2MAPTMAOB | |
| SCHEMBL3147413 | 0.84 | MAOB (0.54) | KDM4EALOX15SMN1; SMN2MAPTMAOB | |
| SCHEMBL18331257 | 0.84 | MAOB (0.54) | KDM4EALOX15SMN1; SMN2MAPTMAOB | |
| SCHEMBL5762073 | 0.82 | MAOB (0.53) | KDM4EMAOBPSMB8PSMB5CA2 | |
| SCHEMBL11500783 | 0.82 | KDM4E (0.51) | KDM4EALOX15SMN1; SMN2MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090293157-A1 | PRODUCTION OF PROGENITOR CEREAL CELLS | CSIR (ZA) | 2009-11-26 | — | — | US | claimed |
| WO-2009093200-A2 | PRODUCTION OF PROGENITOR CEREAL CELLS | CSIR (ZA) | 2009-07-30 | — | — | WO | claimed |
| US-20040237133-A1 | Method for transformation of mono-and di-cotyledonous plants using meristematic tissue and nodal callus from dicotyledonous plants | TOLEDO, UNIVERSITY OF | 2004-11-25 | — | — | US | claimed |
| EP-1455568-A2 | METHOD FOR TRANSFORMATION OF MONO- AND DI- COTYLEDONOUS PLANTS USING MERISTEMATIC TISSUE AND NODAL CALLUS FROM DYCOTILEDONOUS PLANTS | THE UNIVERSITY OF TOLEDO (US) | 2004-09-15 | — | — | EP | claimed |
| WO-2002102979-A2 | TRANSFORMATION OF MONO- AND DI- COTYLEDONOUS PLANTS | UNIVERSITY OF TOLEDO, THE a University instrumentality of the State of Ohio (US) | 2002-12-27 | — | — | WO | claimed |
| JP-7324073-A | — | — | None | — | — | JP | disclosed |
| WO-2025122501-A1 | BENZOTHIOPHENE-3-YL- AND BENZOSELENOPHENE-3-YL (BICLYCLIC HETEROARYL) MALEMIDES AS GSK-3 INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2025-06-12 | — | — | WO | disclosed |
| US-20220007607-A1 | HIGH THROUGHPUT PROTOPLAST ISOLATION AND TRANSFORMATION OF PLANT CELLS FROM A NOVEL LEAF-BASED CELL CULTURE-DERIVED SYSTEM | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2022-01-13 | — | — | US | disclosed |
| CN-112955142-A | Functionalized heterocyclic compounds as antiviral agents | 英安塔制药有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-20200223837-A1 | BENZOFURAN AMIDES AND HETEROAROMATIC ANALOGUES THEREOF FOR USE IN THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2020-07-16 | — | — | US | disclosed |
| US-20200216434-A1 | BENZOFURAN UREAS OR CARBAMATES AND HETEROAROMATIC ANALOGUES THEREOF FOR USE IN THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2020-07-09 | — | — | US | disclosed |
| EP-3638664-A1 | BENZOFURAN AMIDES AND HETEROAROMATIC ANALOGUES THEREOF FOR USE IN THERAPY | European Molecular Biology Laboratory (DE) | 2020-04-22 | — | — | EP | disclosed |
| EP-0048954-B1 | BETA-LACTAM COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-30 | — | — | EP | disclosed |
| EP-0009780-B1 | OCTAHYDRO-1H-BENZO(4,5)FURO(3,2-E)ISOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| US-4260761-A | Intermediates for the preparation of octahydro-1H-benzo[4,5]furo[3,2,-e]-isoquinoline analgesic and narcotic antagonistic compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4243668-A | Octahydro-1H-benzo[4,5]furo[3,2-e]-isoquinoline analgesic and narcotic antagonistic compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| EP-0009780-A2 | Octahydro-1H-benzo(4,5)furo(3,2-e)isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-04-16 | — | — | EP | disclosed |
| US-4172145-A | ANALGESICS, ANTIPYRETICS | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | disclosed |
| US-4172145-A | ANALGESICS, ANTIPYRETICS | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | disclosed |
| US-4126625-A | ANTIPHLOGISTIC, ANALGESIC | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216434-A1 | BENZOFURAN UREAS OR CARBAMATES AND HETEROAROMATIC ANALOGUES THEREOF FOR USE IN THERAPY | NR0B1, NR4A3, NR0B2 | KDM4E 2462/4885ALOX15 339/4885SMN1; SMN2 2277/4885 |
| US-20200223837-A1 | BENZOFURAN AMIDES AND HETEROAROMATIC ANALOGUES THEREOF FOR USE IN THERAPY | SUCNR1, CBR1, CYP2A13 | KDM4E 3266/4885ALOX15 126/4885SMN1; SMN2 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.