Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.69 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.69 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | VHL | P40337 | 6/20 | 0.31 |
| ▸ | ELOC | Q15369 | 4/20 | 0.31 |
| ▸ | ELOB | Q15370 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10221283 | 0.95 | ABCC1 (0.66) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL13083020 | 0.92 | ABCC1 (0.73) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL10271478 | 0.91 | CTSB (0.66) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL14864667 | 0.90 | ABCC1 (0.84) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL10220483 | 0.90 | ABCC1 (0.84) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL10221596 | 0.90 | ABCC1 (0.84) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL10220962 | 0.90 | ABCC1 (0.84) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL10220289 | 0.90 | ABCC1 (0.84) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL10221838 | 0.89 | ABCC1 (0.74) | ABCC1ABCC2ABCG2CTSBPPP3CB | |
| SCHEMBL10221456 | 0.89 | ABCC1 (0.80) | ABCC1ABCC2ABCG2CTSBPPP3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150080569-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-8809266-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130274439-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2013-10-17 | — | — | US | disclosed |
| US-8420597-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20130053577-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2013-02-28 | — | — | US | disclosed |
| US-8283442-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-20120190866-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-8178491-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20090257978-A1 | Antiviral coumpounds | GILEAD SCIENCES, INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274439-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | ABCC1 1980/4885ABCC2 2957/4885ABCG2 1209/4885 |
| US-20090257978-A1 | Antiviral coumpounds | MAVS, ZC3HAV1, EIF2AK2 | ABCC1 905/4885ABCC2 1226/4885ABCG2 1155/4885 |
| US-20130053577-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | ABCC1 1980/4885ABCC2 2957/4885ABCG2 1209/4885 |
| US-20120190866-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | ABCC1 1980/4885ABCC2 2957/4885ABCG2 1209/4885 |
| US-20150080569-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | ABCC1 1980/4885ABCC2 2957/4885ABCG2 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.