⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3330177 | 1.00 | — | — | |
| SCHEMBL10273866 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL18700859 | 0.98 | CHRNA3 (0.44) | — | |
| Hydrochloric Acid SCHEMBL3442784 | 0.98 | CHRNA3 (0.44) | — | |
| Hydrochloric Acid SCHEMBL3442787 | 0.98 | CHRNA3 (0.44) | — | |
| SCHEMBL22018875 | 0.94 | LTA4H (0.42) | — | |
| SCHEMBL12464310 | 0.94 | LTA4H (0.42) | — | |
| SCHEMBL19557798 | 0.91 | CHRNB4 (0.40) | — | |
| SCHEMBL18398793 | 0.86 | CHRNA3 (0.46) | — | |
| SCHEMBL25883074 | 0.85 | CHRNA3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667097-B | Separation of enantiomers of 3-ethylbicyclo [3.2.0] hept-3-en-6-one | 诺瓦色生物公司 | 2021-02-12 | — | — | CN | disclosed |
| EP-3303308-B1 | SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE | NOVASSAY SA (CH) | 2019-10-09 | — | — | EP | disclosed |
| US-10150723-B2 | Separation of enantiomers of 3-ethylbicyclo[3.2.0]hept-3-en-6-one | NOVASSAY S.A. (CH) | 2018-12-11 | — | — | US | disclosed |
| EP-2792664-B1 | OPTICAL RESOLUTION METHOD FOR BICYCLIC COMPOUND USING ASYMMETRIC CATALYST | DAIICHI SANKYO CO LTD (JP) | 2018-07-04 | — | — | EP | disclosed |
| US-20180134643-A1 | SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE | NOVASSAY S.A. (CH) | 2018-05-17 | — | — | US | disclosed |
| EP-3303308-A1 | SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE | Novassay SA (CH) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016146299-A1 | SEPARATION OF ENANTIOMERS OF 3-ETHYLBICYCLO[3.2.0]HEPT-3-EN-6-ONE | NOVASSAY SA (CH) | 2016-09-22 | — | — | WO | disclosed |
| US-9035103-B2 | Optical resolution methods for bicyclic compounds using asymmetric catalysts | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035103-B2 | Optical resolution methods for bicyclic compounds using asymmetric catalysts | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-05-19 | — | — | US | disclosed |
| US-9035103-B2 | Optical resolution methods for bicyclic compounds using asymmetric catalysts | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-05-19 | — | — | US | disclosed |
| US-20130065882-A1 | VLA-4 inhibitory drug | MACHINAGA NOBUO (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20120157437-A1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-06-21 | — | — | US | disclosed |
| EP-2069354-B1 | Aza-benzofuranyl compounds and methods of use | GENENTECH INC (US) | 2011-11-02 | — | — | EP | disclosed |
| US-20110190257-A1 | BICYCLIC HETEROCYCLES AS MEK KINASE INHIBITORS | GENETECH, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| EP-2099796-B1 | AZA-INDOLYL COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2011-06-01 | — | — | EP | disclosed |
| US-20110124622-A1 | ISOINDOLONES DERIVATIVES AS MEK KINASE INHIBITORS AND METHODS OF USE | GENENTECH, INC. (US) | 2011-05-26 | — | — | US | disclosed |
| EP-1499311-B1 | SUBSTITUTED BENZAZOLES AND USE THEREOF AS RAF KINASE INHIBITORS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2009-11-04 | — | — | EP | disclosed |
| WO-2008067481-A1 | AZA-INDOLYL COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008024724-A1 | AZA-BENZOTHIOPHENYL COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008024725-A1 | AZA-BENZOFURANYL COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2008-02-28 | — | — | WO | disclosed |