Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24758464 | 0.78 | ALDH1A1 (0.50) | EPHX2KDM4EHTTPOLBKMT2A | |
| SCHEMBL7778488 | 0.77 | KDM4E (0.57) | EPHX2KDM4EHTTPOLBKMT2A | |
| SCHEMBL15545516 | 0.76 | HTT (0.55) | EPHX2KDM4EHTTPOLBKMT2A | |
| SCHEMBL6891227 | 0.73 | ALDH1A1 (0.62) | EPHX2KDM4EHTTPOLBKMT2A | |
| SCHEMBL7778418 | 0.73 | KDM4E (0.64) | EPHX2KDM4EHTTPOLBKMT2A | |
| SCHEMBL17702625 | 0.71 | KMT2A (0.70) | EPHX2KDM4EHTTPOLBKMT2A | |
| SCHEMBL25561712 | 0.70 | KDM4E (0.44) | EPHX2KDM4EHTTPOLBKMT2A | |
| SCHEMBL482692 | 0.69 | ALDH1A1 (0.49) | EPHX2KMT2ALMNAMEN1 | |
| SCHEMBL19116253 | 0.69 | EPHX2 (0.86) | EPHX2 | |
| SCHEMBL28504782 | 0.68 | KDM4E (0.57) | EPHX2KDM4EHTTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |