Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778488 | 0.83 | KDM4E (0.57) | KDM4EHTTEPHX2POLBHPGD | |
| SCHEMBL15545516 | 0.81 | HTT (0.55) | KDM4EHTTEPHX2POLBHPGD | |
| SCHEMBL17457697 | 0.79 | ALDH1A1 (0.60) | EPHX2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6891227 | 0.79 | ALDH1A1 (0.62) | KDM4EHTTEPHX2POLBMEN1 | |
| SCHEMBL8879807 | 0.78 | KDM4E (1.00) | KDM4EHTTEPHX2POLBHPGD | |
| SCHEMBL24201255 | 0.77 | EPHX2 (0.60) | EPHX2MEN1KMT2AALDH1A1 | |
| SCHEMBL28504782 | 0.76 | KDM4E (0.57) | KDM4EHTTEPHX2POLBHPGD | |
| SCHEMBL1758666 | 0.74 | HTT (0.68) | KDM4EHTTPOLBHPGDMEN1 | |
| SCHEMBL28334704 | 0.74 | KDM4E (0.68) | KDM4EHTTEPHX2POLBHPGD | |
| SCHEMBL16365921 | 0.73 | KDM4E (0.76) | KDM4EHTTEPHX2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477912-B1 | Novel N-acyldipeptides, and pharmaceutical compositions containing the same | UNIV LJUBLJANI (SI) | 2001-08-29 | — | — | EP | disclosed |
| US-5514654-A | ANTITUMOR AGENTS AND IMMUNOMODULATORS | UNIV LJUBLJANI (SI) | 1996-05-07 | — | — | US | disclosed |
| EP-0477912-A2 | Novel N-acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same | UNIVERZA EDVARDA KARDELJA V LJUBLJANI, VDO FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, N.SOL.O., LUBLJANA (YU) | 1992-04-01 | — | — | EP | disclosed |