Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803510 | 0.83 | SLC6A2 (0.41) | NPC1RAB9APDK2SLC6A2SLC6A4 | |
| SCHEMBL883606 | 0.80 | SLC6A2 (0.41) | NPC1RAB9APDK2SLC6A2SLC6A4 | |
| SCHEMBL803191 | 0.79 | TRPM8 (0.40) | MAPTCYP1A2HPGDHTTTRPM8 | |
| SCHEMBL803198 | 0.78 | TRPM8 (0.43) | NPC1RAB9APDK2SLC6A2SLC6A4 | |
| SCHEMBL803189 | 0.77 | TRPM8 (0.43) | NPC1RAB9AMAPTSLC6A2SLC6A4 | |
| SCHEMBL803560 | 0.73 | SLC6A2 (0.42) | NPC1RAB9ACYP3A4PDK2SLC6A2 | |
| SCHEMBL803728 | 0.73 | TRPM8 (0.39) | MAPTLMNACYP1A2CYP2C19TRPM8 | |
| SCHEMBL784980 | 0.73 | SLC6A2 (0.42) | NPC1RAB9ACYP3A4PDK2SLC6A2 | |
| SCHEMBL803577 | 0.72 | TRPM8 (0.43) | CYP1A2CYP2C19SLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL785536 | 0.71 | TRPM8 (0.47) | NPC1RAB9APDK2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |