Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803560 | 0.92 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3TRPM8ALDH1A1 | |
| SCHEMBL784980 | 0.92 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3TRPM8ALDH1A1 | |
| SCHEMBL803766 | 0.87 | TRPM8 (0.47) | SLC6A2SLC6A4SLC6A3TRPM8ALDH1A1 | |
| SCHEMBL785536 | 0.87 | TRPM8 (0.47) | SLC6A2SLC6A4SLC6A3TRPM8ALDH1A1 | |
| SCHEMBL803510 | 0.84 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3TRPM8ALDH1A1 | |
| SCHEMBL803198 | 0.81 | TRPM8 (0.43) | SLC6A2SLC6A4SLC6A3TRPM8ALDH1A1 | |
| SCHEMBL785962 | 0.80 | TRPM8 (0.41) | SLC6A2SLC6A4TRPM8ALDH1A1HPGD | |
| SCHEMBL784631 | 0.80 | TRPM8 (0.41) | SLC6A2SLC6A4TRPM8ALDH1A1HPGD | |
| SCHEMBL803263 | 0.79 | TRPM8 (0.47) | SLC6A2SLC6A4SLC6A3TRPM8PDK2 | |
| SCHEMBL784897 | 0.79 | TRPM8 (0.47) | SLC6A2SLC6A4SLC6A3TRPM8PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |