Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070239 | 0.88 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL15474317 | 0.86 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL27342284 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL241537 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL5689829 | 0.77 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL524836 | 0.77 | — | — | |
| SCHEMBL31324731 | 0.77 | — | — | |
| SCHEMBL3667483 | 0.75 | — | — | |
| SCHEMBL1495985 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL14881486 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898152-B | Preparation method of ethoxy diethyl methylene malonate | 杭州新本立医药有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-113336754-B | Fluorescent probe and preparation method thereof | 天津全和诚科技有限责任公司 | 2022-05-17 | — | — | CN | claimed |
| CN-113336754-A | Fluorescent probe and preparation method thereof | 天津全和诚科技有限责任公司 | 2021-09-03 | — | — | CN | claimed |
| CN-112898152-A | Preparation method of ethoxy diethyl methylene malonate | 杭州新本立医药有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-113336754-B | Fluorescent probe and preparation method thereof | 天津全和诚科技有限责任公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-113735728-A | Preparation method of diethyl aminomalonate hydrochloride | 苏州敬业医药化工有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113336754-A | Fluorescent probe and preparation method thereof | 天津全和诚科技有限责任公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-105980345-B | Method for continuously producing ketomalonic acid compound using flow reactor | 组合化学工业株式会社 | 2019-12-20 | — | — | CN | disclosed |
| CN-110391037-A | It is used to form the composition of electrode, using electrode and solar battery made of it | 三星SDI株式会社 | 2019-10-29 | — | — | CN | disclosed |
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | XU LIFENG (US) | 2012-07-12 | — | — | US | disclosed |
| CN-101061108-A | Novel 4-benzimidazol-2-ylpyridazin-3-one derivatives | AVENTIS PHARMA SA (FR) | 2007-10-24 | — | — | CN | disclosed |
| CN-1326852-C | Benzofuran derivatives | KOWA CO (JP) | 2007-07-18 | — | — | CN | disclosed |
| CN-1759103-A | Water-soluble phenylpyridazine derivative and medicine containing the same | KOWA CO (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1756753-A | Benzofuran derivatives | KOWA CO (JP) | 2006-04-05 | — | — | CN | disclosed |
| CN-1558903-A | Water-soluble phenylpyridazine derivative and drug containing the same | ������������ʽ���� | 2004-12-29 | — | — | CN | disclosed |
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |
| CN-86102877-A | The method for preparing bicyclic pyrazolidinones | — | 1986-10-29 | — | — | CN | disclosed |
| EP-0020173-B1 | IMIDAZOLE GUANIDINES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0020173-A1 | Imidazole guanidines, their preparation and compositions containing them | MERCK & CO. INC. (US) | 1980-12-10 | — | — | EP | disclosed |
| US-4220654-A | Cyclic imidazole cyanoguanidines | MERCK & CO., INC. (US) | 1980-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | TYMP, TYMS, ADORA3 | ALDH1A1 572/4885LMNA 1504/4885HSD17B10 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.