Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 17/20 | 0.44 |
| ▸ | MYB | P10242 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10275842 | 0.88 | NPSR1 (0.48) | NPSR1MYBLNPEPAVPR1B | |
| SCHEMBL10275400 | 0.87 | NPSR1 (0.47) | NPSR1AVPR1B | |
| SCHEMBL10275268 | 0.86 | LNPEP (0.40) | NPSR1MYBLNPEP | |
| SCHEMBL10275509 | 0.86 | NPSR1 (0.41) | NPSR1MYBLNPEPAVPR1B | |
| SCHEMBL10275522 | 0.84 | LNPEP (0.42) | NPSR1MYBLNPEP | |
| SCHEMBL10275498 | 0.82 | NPSR1 (0.46) | NPSR1AVPR1B | |
| SCHEMBL10275541 | 0.79 | NPSR1 (0.39) | NPSR1AVPR1B | |
| SCHEMBL10275263 | 0.77 | NPSR1 (0.40) | NPSR1AVPR1B | |
| SCHEMBL10276274 | 0.77 | MEN1 (0.36) | NPSR1AVPR1B | |
| SCHEMBL10275280 | 0.76 | MEN1 (0.38) | NPSR1LNPEPAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | XU LIFENG (US) | 2012-07-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178915-A1 | PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF | TYMP, TYMS, ADORA3 | NPSR1 1168/4885MYB 4087/4885LNPEP 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.