Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | ITGAL | P20701 | 19/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277590 | 1.00 | TMEM97 (0.61) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL2730098 | 0.92 | TMEM97 (0.62) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL10277216 | 0.88 | TMEM97 (0.61) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL10277214 | 0.88 | TMEM97 (0.61) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL10277384 | 0.88 | TMEM97 (0.60) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL10277382 | 0.88 | TMEM97 (0.60) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL2396246 | 0.88 | TMEM97 (0.63) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL2392351 | 0.86 | TMEM97 (0.62) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL2394785 | 0.86 | ITGAL (0.67) | TMEM97ITGALITGB2ICAM1 | |
| SCHEMBL15998508 | 0.86 | TMEM97 (0.61) | TMEM97ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445914-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2015-07-22 | — | — | EP | disclosed |
| US-8481750-B2 | Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-09 | — | — | US | disclosed |
| US-20120178734-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178734-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | ARG1, COL14A1, HPGDS | TMEM97 3752/4885ITGAL 90/4885ITGB2 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.