Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316063 | 0.85 | ACHE (0.61) | GRIN2BHTR1AACHEGRIN1GRIN2A | |
| SCHEMBL930105 | 0.85 | GRIN2B (0.51) | GRIN2BHTR1AACHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL5782954 | 0.84 | GRIN2B (0.50) | GRIN2BHTR1AACHEGRIN1GRIN2A | |
| SCHEMBL12942834 | 0.83 | GRIN2B (0.52) | GRIN2BHTR1AACHEGRIN1GRIN2A | |
| SCHEMBL927161 | 0.83 | GRIN2B (0.51) | GRIN2BHTR1AACHEGRIN1GRIN2A | |
| SCHEMBL12226577 | 0.82 | GRIN2B (0.48) | GRIN2BHTR1AACHEGRIN1GRIN2A | |
| SCHEMBL918624 | 0.82 | HDAC1 (0.57) | GRIN2BHTR1AACHEGRIN1GRIN2A | |
| SCHEMBL5539610 | 0.82 | GRIN2B (0.53) | GRIN2BHTR1AACHEGRIN1GRIN2A | |
| SCHEMBL10231045 | 0.81 | GRIN2B (0.52) | GRIN2BHTR1ASIGMAR1PARP1 | |
| SCHEMBL929864 | 0.80 | SIGMAR1 (0.67) | GRIN2BHTR1ASIGMAR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | BELLUS HEALTH INC. (CA) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015911-A1 | METHOD AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | APP, PSEN1, PSEN2 | GRIN2B 1832/4885HTR1A 2489/4885ACHE 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.