Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | ACACB | O00763 | 8/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SORD | Q00796 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785317 | 0.84 | PDE10A (0.49) | GBA1ACACBHRH4HRH3 | |
| SCHEMBL27902619 | 0.84 | ACACB (0.46) | ACACBHRH4HRH3SORDOPRD1 | |
| SCHEMBL18166973 | 0.82 | PANK3 (0.46) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL3650736 | 0.82 | TRPV1 (0.46) | HRH4HRH3SORDOPRD1 | |
| SCHEMBL803481 | 0.82 | SIGMAR1 (0.50) | GBA1ACACBHRH3NOS2 | |
| SCHEMBL27920434 | 0.81 | ACACB (0.43) | ACACBHRH4HRH3SORDOPRD1 | |
| SCHEMBL20544124 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10CYP2C19 | |
| SCHEMBL20544053 | 0.81 | HCRTR1 (0.45) | — | |
| SCHEMBL2330983 | 0.81 | ADRB1 (0.53) | ACACBKDM4EALDH1A1 | |
| SCHEMBL20544120 | 0.81 | HRH3 (0.41) | ACACBHRH4HRH3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097354-A | Substituted benzamide compounds | GRUENENTHAL CHEMIE | 2013-05-08 | — | — | CN | disclosed |
| WO-2012038081-A1 | SUBSTITUTED BENZAMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2012-03-29 | — | — | WO | disclosed |