Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27243154 | 0.84 | CES2 (0.50) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL7174103 | 0.84 | CES2 (0.50) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL5279624 | 0.84 | CES2 (0.50) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL349595 | 0.84 | CES2 (0.50) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL27654505 | 0.81 | CES2 (0.47) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL6064356 | 0.79 | CES2 (0.46) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL6666600 | 0.78 | CES2 (0.48) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL6630045 | 0.78 | CES2 (0.48) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL29117890 | 0.78 | TSHR (0.47) | CES2CES1ESR1CYP19A1ESR2 | |
| SCHEMBL27654691 | 0.78 | ESR1 (0.45) | CES2CES1ESR1CYP19A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110089020-A1 | Continuous Method for Producing Amides of Ethylenically Unsaturated Carboxylic Acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-04-21 | — | — | US | disclosed |
| EP-2274273-A1 | CONTINUOUS METHOD FOR PRODUCING AMIDES OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS | Clariant Finance (BVI) Limited (VG) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009121486-A1 | CONTINUOUS METHOD FOR PRODUCING AMIDES OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS | CLARIANT INTERNATIONAL LTD (CH) | 2009-10-08 | — | — | WO | disclosed |
| EP-0249078-A2 | Optically active adsorbents | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |