SCHEMBL27243154

SCHEMBL27243154

CCC(=C(C)C(C)=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
ESR1 P03372 5/20 0.48
ESR2 Q92731 2/20 0.48
CYP19A1 P11511 2/20 0.48
PGR P06401 1/20 0.46
PTGS2 P35354 3/20 0.46
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7174103 0.88 CES2 (0.50) CES2CES1ESR1ESR2CYP19A1
SCHEMBL349595 0.88 CES2 (0.50) CES2CES1ESR1ESR2CYP19A1
SCHEMBL5279624 0.88 CES2 (0.50) CES2CES1ESR1ESR2CYP19A1
SCHEMBL1027804 0.84 CES2 (0.47) CES2CES1ESR1ESR2CYP19A1
SCHEMBL11011931 0.82 CES1 (0.48) CES2CES1MAPTSMN1; SMN2L3MBTL1
SCHEMBL29117890 0.81 TSHR (0.47) CES2CES1ESR1ESR2CYP19A1
SCHEMBL27654691 0.81 ESR1 (0.45) CES2CES1ESR1ESR2CYP19A1
SCHEMBL29117565 0.80 ALDH1A1 (0.54) CES2CES1ESR1ESR2CYP19A1
SCHEMBL27654693 0.80 CES2 (0.43) CES2CES1ESR1ESR2CYP19A1
SCHEMBL3314631 0.79 ESR1 (0.61) CES2CES1ESR1ESR2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199519-A1 ARYL/ALKENYL-PENTENAL DERIVATIVES AS AROMA CHEMICALS BASF SE (DE) 2024-06-20 US disclosed
US-20240199516-A1 DIALKYLPENTENE ETHER AND DIALKYLPENTADIENE ETHER DERIVATIVES AS FRAGRANCES BASF SE (DE) 2024-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199519-A1 ARYL/ALKENYL-PENTENAL DERIVATIVES AS AROMA CHEMICALS AHR, ARNT, TRPA1 CES2 626/4885CES1 2171/4885ESR1 262/4885
US-20240199516-A1 DIALKYLPENTENE ETHER AND DIALKYLPENTADIENE ETHER DERIVATIVES AS FRAGRANCES DEK, TRPA1, DGKI CES2 534/4885CES1 1109/4885ESR1 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.