Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354540 | 0.91 | ROCK1 (0.46) | ROCK1ROCK2 | |
| SCHEMBL10278978 | 0.87 | ROCK1 (0.44) | ROCK1ROCK2 | |
| SCHEMBL10279303 | 0.83 | ROCK1 (0.44) | ROCK1ROCK2 | |
| SCHEMBL10279478 | 0.82 | ROCK1 (0.44) | ROCK1ROCK2 | |
| SCHEMBL353214 | 0.79 | ROCK1 (0.48) | ROCK1ROCK2 | |
| SCHEMBL351643 | 0.78 | ROCK1 (0.49) | ROCK1ROCK2 | |
| SCHEMBL353373 | 0.77 | ROCK1 (0.47) | ROCK1ROCK2 | |
| SCHEMBL353663 | 0.76 | KMT2A (0.51) | ROCK1ROCK2 | |
| SCHEMBL4777145 | 0.76 | SCD (0.51) | ROCK1ROCK2 | |
| SCHEMBL4726379 | 0.75 | TSHR (0.51) | ROCK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | ROCK1 4747/4885ROCK2 4626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.