Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022579 | 0.95 | RORC (0.70) | RORC | |
| SCHEMBL10280250 | 0.95 | RORC (0.70) | RORC | |
| SCHEMBL10280247 | 0.91 | RORC (0.79) | RORC | |
| SCHEMBL5021992 | 0.91 | RORC (0.79) | RORC | |
| SCHEMBL10280233 | 0.90 | RORC (0.66) | RORC | |
| SCHEMBL10280234 | 0.89 | RORC (0.65) | RORC | |
| SCHEMBL15625835 | 0.88 | RORC (0.84) | RORC | |
| SCHEMBL5022590 | 0.87 | RORC (0.60) | RORC | |
| SCHEMBL5022507 | 0.87 | RORC (0.70) | RORC | |
| SCHEMBL5022530 | 0.86 | RORC (0.58) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064744-A2 | TETRAHYDROQUINOLINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORϒ ACTIVITY AND THE TREATMENT OF DISEASE | LYCERA CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |