Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.79 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | RORA | P35398 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | RORB | Q92753 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5021992 | 1.00 | RORC (0.79) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL5022507 | 0.94 | RORC (0.70) | RORC | |
| SCHEMBL5022579 | 0.94 | RORC (0.70) | RORC | |
| SCHEMBL10280250 | 0.94 | RORC (0.70) | RORC | |
| SCHEMBL5023349 | 0.92 | RORC (0.81) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL10280233 | 0.91 | RORC (0.66) | RORC | |
| SCHEMBL10280237 | 0.91 | RORC (0.66) | RORC | |
| SCHEMBL5022528 | 0.91 | RORC (0.68) | RORC | |
| SCHEMBL10280235 | 0.90 | RORC (0.79) | RORC | |
| SCHEMBL5023788 | 0.90 | RORC (0.79) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064744-A2 | TETRAHYDROQUINOLINE AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORϒ ACTIVITY AND THE TREATMENT OF DISEASE | LYCERA CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |