Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280737 | 0.93 | TBK1 (0.34) | TBK1GCKDGAT1 | |
| SCHEMBL563669 | 0.92 | GCK (0.35) | TBK1GCKDGAT1 | |
| SCHEMBL564824 | 0.92 | GCK (0.34) | TBK1GCKDGAT1 | |
| SCHEMBL565004 | 0.91 | GCK (0.35) | TBK1GCKDGAT1 | |
| SCHEMBL564572 | 0.90 | GCK (0.35) | TBK1GCKDGAT1 | |
| SCHEMBL564431 | 0.90 | GCK (0.33) | TBK1GCK | |
| SCHEMBL10280306 | 0.89 | GCK (0.34) | TBK1GCKDGAT1 | |
| SCHEMBL565067 | 0.88 | GCK (0.33) | TBK1GCK | |
| SCHEMBL12196145 | 0.87 | GCK (0.31) | TBK1GCK | |
| SCHEMBL12807202 | 0.86 | GCK (0.32) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035163-A1 | NOVEL FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035163-A1 | NOVEL FUSED RING COMPOUND AND USE THEREOF | GPR119, GCKR, SLC5A1 | TBK1 2600/4885GCK 5/4885DGAT1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.