SCHEMBL10280728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15426412	0.93	POLB (0.36)	POLBPDE10APDE2AHSD11B1S1PR1
	SCHEMBL10281047	0.92	POLB (0.42)	POLBPDE10APDE2A
	SCHEMBL10281057	0.91	POLB (0.41)	POLBPDE2AHSD11B1CNR2
	SCHEMBL10280733	0.91	POLB (0.41)	POLBMAOBPDE2A
	SCHEMBL15412786	0.89	POLB (0.43)	POLBPDE10AMAOBPDE2AHSD11B1
	SCHEMBL15427213	0.89	POLB (0.40)	POLB
	SCHEMBL15616836	0.88	POLB (0.41)	POLBPDE10APDE2ACRHR1CYP1A2
	SCHEMBL116987	0.88	POLB (0.42)	POLBPDE10APDE2AGRIN1GRIN2B
	SCHEMBL17824437	0.88	POLB (0.42)	POLBPDE10AHSD11B1
	SCHEMBL16622982	0.85	POLB (0.42)	POLBPDE10APDE2AGRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.