Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | GCG | P01275 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389950 | 0.90 | GPBAR1 (0.61) | GPBAR1 | |
| SCHEMBL1390115 | 0.87 | GPBAR1 (0.57) | GPBAR1NAMPT | |
| SCHEMBL1389995 | 0.85 | GPBAR1 (0.63) | GPBAR1EPHX2 | |
| SCHEMBL1389999 | 0.85 | GPBAR1 (0.63) | GPBAR1EPHX2 | |
| SCHEMBL363824 | 0.85 | GPBAR1 (0.63) | GPBAR1EPHX2 | |
| SCHEMBL1389784 | 0.85 | GPBAR1 (0.67) | GPBAR1 | |
| SCHEMBL1389782 | 0.85 | GPBAR1 (0.67) | GPBAR1 | |
| SCHEMBL362992 | 0.85 | GPBAR1 (0.67) | GPBAR1 | |
| SCHEMBL1389968 | 0.83 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL362388 | 0.83 | GPBAR1 (0.64) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010190-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010190-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | GPBAR1, GPR119, ADRB1 | GPBAR1 1/4885EPHX2 1909/4885NAMPT 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.