Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 6/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.30 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18520303 | 0.86 | DPP4 (0.44) | DPP4SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17992932 | 0.82 | DPP4 (0.47) | DPP4SLC7A5 | |
| SCHEMBL26343503 | 0.82 | DPP4 (0.47) | DPP4SLC7A5 | |
| SCHEMBL3124635 | 0.79 | SLC7A5 (0.44) | DPP4SLC7A5SLC1A3SLC1A2ANPEP | |
| SCHEMBL15730402 | 0.79 | RNPEP (0.34) | SLC7A5SLC1A3SLC1A2ALDH1A1CACNA2D1 | |
| SCHEMBL3045850 | 0.78 | DPP4 (0.45) | DPP4SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL3045853 | 0.78 | DPP4 (0.45) | DPP4SLC7A5SLC1A3SLC1A2 | |
| SCHEMBL23001270 | 0.72 | ALDH1A1 (0.36) | SLC7A5SLC1A3SLC1A2ALDH1A1CACNA2D1 | |
| SCHEMBL16054205 | 0.71 | SLC7A5 (0.52) | DPP4SLC7A5SLC1A3SLC1A2LAP3 | |
| SCHEMBL1953318 | 0.71 | DPP4 (0.52) | DPP4SLC7A5SLC1A3SLC1A2LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021796-A2 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL, INC. (US) | 2012-02-16 | — | — | WO | disclosed |