Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 5/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27244999 | 0.85 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL27244993 | 0.85 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL31042489 | 0.82 | SLC7A5 (0.43) | SLC7A5DPP4SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10280902 | 0.79 | DPP4 (0.46) | SLC7A5DPP4SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11568275 | 0.78 | SLC7A5 (0.40) | SLC7A5DPP4SLC1A3SLC1A2SLC1A1 | |
| Trifluoroacetic Acid SCHEMBL30890611 | 0.77 | SLC7A5 (0.39) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| Trifluoroacetic Acid SCHEMBL27244741 | 0.77 | SLC7A5 (0.39) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL18125957 | 0.77 | RNPEP (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL30116852 | 0.76 | MMP2 (0.36) | SLC7A5SLC1A3SLC1A2RNPEPMMP2 | |
| SCHEMBL4966689 | 0.76 | SLC7A5 (0.38) | SLC7A5DPP4SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560558-B1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2010-12-29 | — | — | EP | disclosed |
| EP-1387660-B1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2010-07-14 | — | — | EP | disclosed |
| US-6987090-B2 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1339378-A4 | USE OF CYCLOSPORIN A 7-THIOAMIDE DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2004-05-12 | — | — | EP | disclosed |
| US-20040087496-A1 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-06 | — | — | US | disclosed |
| US-20040071650-A1 | Use of cyclosporin 7-thioamide derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-04-15 | — | — | US | disclosed |
| EP-1339378-A1 | USE OF CYCLOSPORIN A 7-THIOAMIDE DERIVATIVES FOR HAIR GROWTH | LG Household & Health Care Ltd. (KR) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002041859-A1 | USE OF CYCLOSPORIN A 7-THIOAMIDE DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087496-A1 | Use of 3-position cyclosporin derivatives for hair growth | TPMT, BHMT2, SUCLG1 | SLC7A5 539/4885DPP4 4694/4885SLC1A3 1781/4885 |
| US-20040071650-A1 | Use of cyclosporin 7-thioamide derivatives for hair growth | CYP2A7, TST, PPP1R7 | SLC7A5 1717/4885DPP4 4319/4885SLC1A3 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.