Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922478 | 0.87 | CA1 (0.37) | CA1CA2CA7CA9 | |
| SCHEMBL350286 | 0.81 | CA1 (0.46) | CA1CA2CA7CA9PDE10A | |
| SCHEMBL18922603 | 0.79 | CA1 (0.35) | CA1CA2CA7CA9 | |
| SCHEMBL18922610 | 0.78 | NSD2 (0.40) | — | |
| SCHEMBL10280915 | 0.78 | TP53 (0.30) | — | |
| SCHEMBL10280940 | 0.78 | CA1 (0.34) | CA1CA2CA7CA9 | |
| SCHEMBL18922613 | 0.77 | NPC1 (0.33) | — | |
| SCHEMBL10280970 | 0.77 | CA1 (0.40) | CA1CA2CA7CA9PDE10A | |
| SCHEMBL20862867 | 0.76 | CA1 (0.41) | CA1CA2CA7CA9PDE10A | |
| SCHEMBL18922437 | 0.73 | NSD2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669399-B2 | Phosphine ligands for catalytic reactions | ABBVIE INC. (US) | 2017-06-06 | — | — | US | disclosed |
| WO-2012009698-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |