Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922610 | 0.90 | NSD2 (0.40) | NSD2ALDH1A1EGFRLMNAMAPT | |
| SCHEMBL18922603 | 0.84 | CA1 (0.35) | NSD2ALDH1A1EGFRLMNAMAPT | |
| SCHEMBL18922613 | 0.82 | NPC1 (0.33) | ALDH1A1LMNAMAPT | |
| SCHEMBL351835 | 0.79 | ALDH1A1 (0.37) | NSD2ALDH1A1EGFRLMNAMAPT | |
| SCHEMBL18922478 | 0.76 | CA1 (0.37) | ALDH1A1EGFRLMNAMAPTMAPK1 | |
| SCHEMBL10281272 | 0.75 | — | — | |
| SCHEMBL10280892 | 0.75 | ABL1 (0.40) | MAPT | |
| SCHEMBL10280966 | 0.73 | CA1 (0.41) | — | |
| SCHEMBL10280915 | 0.73 | TP53 (0.30) | — | |
| SCHEMBL352694 | 0.69 | L3MBTL1 (0.45) | NSD2ALDH1A1EGFRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669399-B2 | Phosphine ligands for catalytic reactions | ABBVIE INC. (US) | 2017-06-06 | — | — | US | disclosed |