Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350286 | 0.92 | CA1 (0.46) | CA1CA2CA7CA9PDE10A | |
| SCHEMBL351987 | 0.79 | CA1 (0.42) | CA1CA2CA7CA9 | |
| SCHEMBL10280966 | 0.77 | CA1 (0.41) | CA1CA2CA7CA9PDE10A | |
| SCHEMBL20862867 | 0.75 | CA1 (0.41) | CA1CA2CA7CA9PDE10A | |
| SCHEMBL350457 | 0.73 | CA1 (0.38) | CA1CA2CA7CA9 | |
| SCHEMBL24535424 | 0.72 | TDP2 (0.33) | CA1CA2CA7CA9 | |
| SCHEMBL10177358 | 0.72 | ALDH1A1 (0.39) | CA1CA2CA7CA9 | |
| SCHEMBL10227457 | 0.71 | CA1 (0.41) | CA1CA2CA7CA9ADRA2B | |
| SCHEMBL351057 | 0.70 | CA1 (0.39) | CA1CA2CA7CA9 | |
| SCHEMBL17284075 | 0.70 | CA1 (0.35) | CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009698-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |