Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365324 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL18922613 | 0.76 | NPC1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL10280972 | 0.73 | — | — | |
| SCHEMBL18922437 | 0.72 | NSD2 (0.33) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL18922478 | 0.70 | CA1 (0.37) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL18922610 | 0.70 | NSD2 (0.40) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL10280892 | 0.69 | ABL1 (0.40) | MEN1KMT2A | |
| SCHEMBL410812 | 0.66 | MAPK1 (0.41) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL18922603 | 0.65 | CA1 (0.35) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL407632 | 0.61 | MAPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009698-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |