Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25649498 | 0.77 | AKT1 (0.40) | AKT1 | |
| SCHEMBL12831681 | 0.75 | CES2 (0.52) | — | |
| SCHEMBL12802064 | 0.75 | TDP1 (0.52) | — | |
| SCHEMBL21417238 | 0.75 | F2 (0.48) | AKT1 | |
| SCHEMBL12095541 | 0.75 | TP53 (0.52) | AKT1 | |
| SCHEMBL12449810 | 0.75 | APP (0.36) | AKT1 | |
| SCHEMBL14046813 | 0.74 | L3MBTL1 (0.36) | — | |
| SCHEMBL108144 | 0.72 | AKT1 (0.54) | AKT1 | |
| SCHEMBL20934481 | 0.72 | UNG (0.36) | AKT1 | |
| SCHEMBL23015482 | 0.71 | PTGS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307372-B1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2012-04-25 | — | — | EP | disclosed |