Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929663 | 0.83 | KMT2A (0.62) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL4530091 | 0.82 | KMT2A (0.50) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL18388562 | 0.82 | KMT2A (0.47) | MEN1KMT2ALMNACYP2C19 | |
| Heptabarbital SCHEMBL713359 | 0.78 | MEN1 (0.43) | MEN1KMT2ALMNAALDH1A1 | |
| Cyclobarbital SCHEMBL157224 | 0.76 | MEN1 (0.44) | MEN1KMT2ALMNAALDH1A1 | |
| Cyclobarbital SCHEMBL1256543 | 0.75 | MEN1 (0.43) | MEN1KMT2ALMNAALDH1A1 | |
| Cyclobarbital SCHEMBL7698655 | 0.74 | MEN1 (0.42) | MEN1KMT2ALMNA | |
| Heptabarbital SCHEMBL1649324 | 0.71 | MEN1 (0.38) | MEN1KMT2A | |
| SCHEMBL17791220 | 0.70 | LMNA (0.66) | MEN1KMT2ALMNAMAPTCYP2C19 | |
| Mephobarbital SCHEMBL4261724 | 0.69 | LMNA (0.65) | MEN1KMT2ALMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-07-12 | — | — | US | disclosed |
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-07-12 | — | — | US | disclosed |
| US-20160024011-A1 | Multi-API Loading Prodrugs | ALKERMES PHARMA IRELAND LTD (IE) | 2016-01-28 | — | — | US | disclosed |
| US-20120202823-A1 | Multi-API Loading Prodrugs | ALKERMES, INC. | 2012-08-09 | — | — | US | disclosed |
| WO-2012088441-A1 | MULTI- API LOADING PRODRUGS | ALKERMES, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024011-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | MEN1 2927/4885KMT2A 652/4885LMNA 2855/4885 |
| US-20120202823-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | MEN1 2927/4885KMT2A 652/4885LMNA 2855/4885 |
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | AADAC, PAICS, ABCG2 | MEN1 2927/4885KMT2A 652/4885LMNA 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.