Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929663 | 0.86 | KMT2A (0.62) | KMT2AMEN1LMNACYP2C19HCAR2 | |
| SCHEMBL18388562 | 0.85 | KMT2A (0.47) | KMT2AMEN1LMNACYP2C19HCAR2 | |
| SCHEMBL10281101 | 0.82 | MEN1 (0.45) | KMT2AMEN1LMNACYP2C19ALDH1A1 | |
| Cyclobarbital SCHEMBL157224 | 0.81 | MEN1 (0.44) | KMT2AMEN1LMNAHCAR2ALDH1A1 | |
| Cyclobarbital SCHEMBL1256543 | 0.80 | MEN1 (0.43) | KMT2AMEN1LMNAHCAR2ALDH1A1 | |
| Heptabarbital SCHEMBL713359 | 0.80 | MEN1 (0.43) | KMT2AMEN1LMNAHCAR2ALDH1A1 | |
| Cyclobarbital SCHEMBL7698655 | 0.79 | MEN1 (0.42) | KMT2AMEN1LMNAHCAR2TSHR | |
| Mephobarbital SCHEMBL4261724 | 0.73 | LMNA (0.65) | KMT2AMEN1LMNACYP2C19TSHR | |
| Heptabarbital SCHEMBL1649324 | 0.73 | MEN1 (0.38) | KMT2AMEN1HCAR2 | |
| Cyclobarbital SCHEMBL5458050 | 0.71 | HCAR2 (0.40) | KMT2AMEN1LMNAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557175-B2 | Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-07-07 | — | — | US | disclosed |
| WO-2008136842-A1 | POLY( CARBONATE-CO-UREA) COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008136841-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-11-13 | — | — | WO | disclosed |