Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 7/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | BECN1 | Q14457 | 4/20 | 0.43 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10006033 | 0.90 | PTGER2 (0.41) | LIPENAMPTBRD4CREBBPPSMB8 | |
| SCHEMBL10281527 | 0.78 | KDM1A (0.46) | KDM1AMAOBBCL2LIPEBECN1 | |
| SCHEMBL9939438 | 0.77 | PTGER2 (0.47) | — | |
| SCHEMBL10298879 | 0.74 | BCL2 (0.44) | KDM1AMAOBBCL2BECN1SLC10A2 | |
| SCHEMBL612556 | 0.74 | ESR2 (0.47) | LIPEDRD2NAMPTBRD4CREBBP | |
| SCHEMBL34466750 | 0.74 | FFAR1 (0.46) | KDM1AMAOBMAOA | |
| SCHEMBL10281197 | 0.73 | MAOB (0.41) | KDM1AMAOBBCL2BECN1SLC10A2 | |
| SCHEMBL21148556 | 0.73 | BRD4 (0.47) | KDM1ALIPEDRD2NAMPTBRD4 | |
| SCHEMBL775002 | 0.73 | NAMPT (0.56) | LIPEDRD2NAMPTPSMB8 | |
| SCHEMBL10298882 | 0.72 | SLC6A3 (0.41) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083170-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-06-21 | — | — | WO | disclosed |