⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282542 | 1.00 | — | — | |
| SCHEMBL1719954 | 1.00 | — | — | |
| SCHEMBL1742998 | 0.90 | LMNA (0.58) | — | |
| SCHEMBL2348889 | 0.88 | — | — | |
| Ethambutol SCHEMBL4029 | 0.82 | LMNA (1.00) | — | |
| Ethambutol SCHEMBL2636850 | 0.82 | LMNA (1.00) | — | |
| Ethambutol SCHEMBL15479016 | 0.82 | LMNA (1.00) | — | |
| Ethambutol SCHEMBL3399 | 0.82 | LMNA (1.00) | — | |
| Ethambutol SCHEMBL2961583 | 0.82 | LMNA (1.00) | — | |
| Ethambutol SCHEMBL9906602 | 0.82 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2535345-A1 | Anticancer nucleoside analogs | BioCryst Pharmaceuticals, Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| US-8097708-B2 | 10a-Azalide compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090281292-A1 | 10a-Azalide Compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20070293511-A1 | Crf Receptor Antagonists and Methods | SB PHARMCO PUERTO RICO INC. AND NEUROCRINE BIOSCIENCES, INC., A CORPORATION | 2007-12-20 | — | — | US | disclosed |