Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4618408 | 0.98 | NPC1 (0.72) | NPC1RAB9ATSHRHPGDAKR1C1 | |
| SCHEMBL5392782 | 0.91 | NPC1 (0.66) | NPC1RAB9ATSHRHPGDAKR1C1 | |
| SCHEMBL4310722 | 0.85 | TSHR (0.84) | NPC1RAB9ATSHRHPGDAKR1C1 | |
| SCHEMBL7302754 | 0.84 | NPC1 (0.72) | NPC1RAB9ATSHRHPGDAKR1C1 | |
| SCHEMBL27297526 | 0.82 | NPC1 (0.70) | NPC1RAB9ATSHRHPGDAKR1C1 | |
| SCHEMBL7218802 | 0.82 | HPGD (0.73) | NPC1RAB9ATSHRHPGDAKR1C1 | |
| SCHEMBL1136719 | 0.82 | L3MBTL3 (0.59) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL9193006 | 0.81 | TSHR (0.72) | NPC1RAB9ATSHRHPGDAKR1C1 | |
| SCHEMBL11986399 | 0.81 | NPC1 (0.72) | NPC1RAB9ATSHRHPGDAKR1C1 | |
| SCHEMBL408393 | 0.81 | NPC1 (0.72) | NPC1RAB9ATSHRHPGDAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | HAVCR2, ZC3HAV1, MAVS | NPC1 196/4885RAB9A 2965/4885TSHR 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.